Abstract: This study investigated the influence of administrative strategies on the effective management of human resources in secondary schools in Ondo State, Nigeria. As a descriptive survey, the study population comprised all the 281 public secondary schools in the State. Out of this population, a sample of 225 schools was selected. Out of the 6241 teachers and 3,564 non-teaching staff in the sample, 1220 respondents, made up of 782 teachers and 438 non-teaching staff were selected through the multi-stage and stratified random sampling techniques. The instrument used for the study was a questionnaire. Returns were however received from 980 respondents, made up of 624 teachers and 356 non-teaching staff (80.3%). The data collected were analyzed using percentages, t-test one way analysis of variance and multiple regression. The findings showed that the level of human resources management by school principals was low. There was no significant difference between the management of teaching and non-teaching staff. There was however a better management of human resources in small schools than in large schools. There was also a better management of human resources in rural schools than in urban schools. Based on the findings, it was recommended that principals should equip themselves adequately with the effective use of administrative strategies such as effective supervision, monitoring, communication, proper delegation of duty, effective leadership, motivation and effective discipline to enhance better human resources management in their schools. The State Government should intensify efforts in training and retraining principals and conducting seminars and refreshers courses for principals, teachers and non-teaching staff on strategies of managing human resources in schools.