Abstract: This study is intended to evaluate the validity, practicality and effectiveness of learning device development in accordance with environmental pollution in Madrasah Aliyah. What is meant by learning device is a syllabus, lesson plans, worksheets and key answers, assessment sheets and key answers as well as teaching materials. In this study, Mafumiko Model was chosen in order to determine the development measures such as expert opinion, small class and big class test and lastly, expert opinion through panel sessions. Moreover, this study used a descriptive quantitative research method in its implementation. The subjects of the research are three professors of biology, individual test (one to one) and a small class of students in first year class, also other field trials from different students in the other 2 classes. This study was carried out for 6 months (April-September 2015) and the data validity was obtained from the expert team decision conducted by using the format of learning device validation rating. In the other hand, the practicality data was generated from the observer point of view on the learning assessment implemented by teacher with lesson plan format. Meanwhile, the effectiveness data was derived from: cognitive tests, performance skills observation, psychomotor skills observation, spiritual attitudes observation, character observation, social attitudes observation, critical thinking skills test, student activity during learning activity observation and teacher activity during learning activity observation. Then, the analysis was established descriptively and it produced a valid, practical and effective result. The result showed teachers were capable in implementing the learning activities. Based on the efficiency parameters, this study showed that the learning device was in a good category.