References

Albareda, M., J. Rodriguez-Espinosa, M. Murugo, A. de Leiva and R. Corcoy, 2000. Assessment of insulin sensitivity and beta-cell function from measurements in the fasting state and during an oral glucose tolerance test. Diabetologia, 43: 1507-1511.

Althuis, M.D., N.E. Jordan, E.A. Ludington and J.T. Wittes, 2002. Glucose and insulin responses to dietary chromium supplements: A meta-analysis. Am. J. Clin. Nutr., 76: 148-155.
Direct Link  |  

Anderson, R.A., M.M. Polansky, N.A. Bryden and J.J. Canary, 1991. Supplemental chromium effects on glucose, insulin, glucagon, and urinary chromium losses in subjects consuming controlled low-chromium diets. Am. J. Clin. Nutr., 54: 909-916.
PubMed  |  

Anderson, R.A., M.M. Polansky, N.A. Bryden, E.E. Roginski, K.Y. Patterson, and D.C. Reamer, 1982. Effect of exercise (running) on serum glucose, insulin, glucagon and chromium excretion. Diabetes, 31: 212-216.

Anderson, R.A., M.M. Polansky, N.A. Bryden, E.E. Roginski, W. Mertz and W. Glinsmann, 1983. Chromium supplementation of human subjects: Effects on glucose, insulin and lipid variables. Metabolism, 32: 894-899.
PubMed  |  

Anderson, R.A., N.C. Cheng, N.A. Bryden, M.M. Polansky and N. Cheng, 1997. Elevated levels of supplemental chromium improve glucose and insulin in individuals with type 2 diabetes. Diabetes, 46: 1786-1791.
PubMed  |  

Balk, E.M., A. Tatsioni, A.H. Lichtenstein, J. Lau and A.G. Pittas, 2007. Effect of chromium supplementation on glucose metabolism and lipids: A systematic review of randomized controlled trials. Diabetes Care, 30: 2154-2163.
Direct Link  |  

Chung, K.H., M.H. Kang, C.S. Kim, I.K. Han and K.N. Lee, 1983. The toxicity of trivalent chromium and its interaction with cobalt and zinc in the chick. Korean J. Anim. Sci., 25: 686-691.

Clodfelder, B.J. and J.B. Vincent, 2005. The time-dependent transport of chromium in adult rats from the blood stream to the urine. J. Biol. Inorg. Chem., 10: 383-393.
PubMed  |  

Crawford, V., R. Scheckenbach and H.G. Preuss, 1999. Effects of niacin-bound chromium supplementation on body composition in overweight African-American women. Diabetes Obes. Metab., 1: 331-337.
PubMed  |  

Davis, C.M. and J.B. Vincent, 1997. Chromium oligopeptide activates insulin receptor tyrosine kinase activity. Biochemistry, 36: 4382-4385.
PubMed  |  

Davis, C.M. and J.B. Vincent, 1997. Isolation and characterization of a biologically active chromium oligopeptide from bovine liver. Arch. Biochem. Biophys., 339: 335-343.
CrossRef  |  

Elliott, S.S., N.L. Keim, J.S. Stern, K. Teff and P.J. Havel, 2002. Fructose, weight gain and the insulin resistance syndrome. Am. J. Clin. Nutr., 76: 911-922.
PubMed  |  Direct Link  |  

Fried S.K., D.A. Bunkin and A.S. Greenberg, 1998. Omental and subcutaneous adipose tissues of obese subjects release interleukin�6: Depot difference and regulation by glucocorticoid. Endocrinol. Metab., 83: 847-850.
PubMed  |  

Gosh, D., B. Bhattacharya, B. Mukherjee, B. Manna, M. sinha, J. Chowdhury and S. Chowdhury, 2002. Role of chromium supplementation in indian with type 2 diabets mellitus. J. Nutr. Biochem., 13: 690-697.
PubMed  |  

Hansen, E., T. Hajri and N.N. Abumrad, 2006. Is all fat the same? The role of fat in the pathogenesis of the metabolic syndrome and type 2 diabetes mellitus. Surgery, 139: 711-716.
PubMed  |  

Hatfield, M.J., G. Shanna, Y. Chen, Z. Li, C.J. Cassady and J.B. Vincent, 2006. Low-molecular-weight chromium-binding substance from chicken liver and American alligator liver. Compar. Biochem. Physiol., 144: 423-431.
PubMed  |  

Hepburn, D.D.D., J.M. Burney, S.A. Woski and J.B. Vincent, 2003. The nutritional supplement chromium picolinate generates oxidative DNA damage and peroxidized lipids in vivo. Polyhedron, 22: 455-463.
Direct Link  |  

Heronenberg, H.M., S. Melmed, K. Polonsky and P.R. Larsen, 2008. Williams Text Book of Endocrinology. Elsevier, Saunders, Canada.

Hotamisligil, G.S., P. Peraldi, A. Budavari, R. Ellis, M.F. White and B.M. Spiegelman, 1996. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Sci., 271: 665-670.
CrossRef  |  

Jalal, R., S.M. Bagheri, A. Moghimi and M.B. Rasuli, 2007. Hypoglycemic effect of aqueous shallot and garlic extracts in rats with fructose-induced insulin resistance. J. Clin. Biochem. Nutr., 41: 218-223.
CrossRef  |  PubMed  |  Direct Link  |  

Jeejeebhoy, K.N., 1999. Chromium and parenteral nutrition. J. Trace Elements Exp. Med., 12: 85-89.
Direct Link  |  

Jorhem, L., 2000. Determination of metals in foods by atomic absorption spectrometry after dry ashing: NMKL¹ collaborative study. J. AOAC Int., 83: 1204-1211.
PubMed  |  Direct Link  |  

Juan, C.C., L.C. Au, V.S. Fang and S. Kang, 2001. Suppressed gene expression of adipocyte resistin in an insulin- resistant rat model. Bio Chem. Bio Phys. Res. Commun., 289: 1328-1333.
PubMed  |  

Kandror, K.V., 1999. Insulin regulation of protein traffic in rat adipose cells. J. Biol. Chem., 274: 25210-25217.
Direct Link  |  

Kozlovsky, A.S., P.B. Moser, R.A. Reisner and R.A. Anderson, 1986. Effect of diets high in simple sugars on urinary chromium losses. Metabolism, 35: 515-518.
PubMed  |  

Kuryl, T., Z. Krejpcio, R.W. W�jciak, M. Lipko, B. Debski and H. Staniek, 2006. Chromium (iii) propionate and dietary fructans supplementation stimulate erythrocyte glucose uptake and beta-oxidation in lymphocytes of rats. Biol. Trace Element Res., 114: 237-248.
CrossRef  |  Direct Link  |  

Le, K.A. and L. Tappy, 2006. Metabolic effects of fructose. Curr. Opin. Clin. Nutr. Metab. Care, 9: 469-475.
CrossRef  |  PubMed  |  Direct Link  |  

Lionetti, L., M.P. Mollica, A. Lombardi, G. Cavaliere, G. Gifuni and A. Barletta, 2009. From chronic over nutrition to insulin resistance: The role of fat-storing capacity and inflammation. Nutr. Metab. Cardiovascular Dis., 19: 146-152.
PubMed  |  

Martin, J., Z.Q. Wang, X.H. Zhang, D. Wachtel, J. Volaufova, D.E. Matthews and W.T. Cefalu, 2006. Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes. Diabetes Care, 29: 1826-1832.
PubMed  |  

Mertz, W., E.E. Roginski and K. Schwarz, 1961. Effect of trivalent chromium complexes on glucose uptake by epididymal fat tissue of rats. J. Biol. Chem., 336: 318-322.
Direct Link  |  

Morris, B.W., S. MacNeil, C.A. Hardisty, S. Heller, C. Burgin and T. Gray, 1999. Chromium homeostasis in patients with type II (NIDDM) diabetes. J. Trace Elements Med Biol., 13: 57-61.

Morris, B.W., S. MacNeil, K. Stanley, T.A. Gray and R. Fraser, 1993. The inter-relationship between insulin and chromium in hyperinsulinaemic euglycaemic clamps in healthy volunteers. J. Endocrinol., 139: 339-345.
Direct Link  |  

NRC, BA, CAN and LAN, 1995. Nutrient Requirements of Laboratory Animals. 4th Edn., National Academy Press, Washington, DC, United State, ISBN-13: 9780309051262, Pages: 192.

National Research Council, 2005. Mineral Tolerance of Animals. National Academy Press, Washington DC.

Rabinovitz, H., A. Friedensohn, A. Leibovitz, G. Gabay, C. Rocas and B. Habot, 2004. Effect of chromium supplementation on blood glucose and lipid levels in type 2 diabetes mellitus elderly patients. Int. J. Vitam. Nutr. Res., 74: 178-182.
PubMed  |  

SAS, 1996. SAS Institute: SAS User`s Guide: Statistics. SAS Institute Inc., Cary, NC.

Smith, K.L., M.R. Waldron, J.K. Drackley, M.T. Socha and T.R. Overton, 2005. Performance of dairy cows as affected by prepartum dietary carbohydrate source and supplementation with chromium throughout the transition period. J. Dairy Sci., 88: 255-263.
CrossRef  |  PubMed  |  Direct Link  |  

Snedecor, G. and W. Cochran, 1991. Statistical Methods. 8th Edn., Iowa state University press, Ames, IA.

Sreekanth, R., V. Pattabhi and S.S. Rajan, 2008. Molecular basis of chromium insulin interactions. Biochem. Biophys. Res. Comm., 369: 725-729.
CrossRef  |  

Sumner, J.M., F. valdz and J.P. McNamara, 2007. Effect of chromium propionate on response to an intravenous glucose tolerance test in growing Holstein heifers. J. Dairy Sci., 90: 3467-3474.
Direct Link  |  

Sun, Y., B.J. Clodfelder, A.A. Shute, T. Irvin and J.B. Vincent, 2002. The biomimetic [Cr3O (O2CCH2CH3)6 (H2O) 3] + decreases plasma insulin, cholesterol and triglycerides in healthy and type 2 diabetic rats but not type 1 diabetic rats. J. Biol. Inorg. Chem., 7: 852-862.
CrossRef  |  

Vincent, J.B., 2000. Elucidating a biological role for chromium at a molecular level. Acc. Chem. Res., 33: 503-510.
PubMed  |  

Vincent, J.B., 2004. Recent advances in the nutritional biochemistry of trivalent chromium. Proc. Nutr. Soc., 63: 41-47.
PubMed  |  

Wallace, T., J.C. Levy and D.R. Matthews, 2004. Use and abuse of HOMA modeling. Diabetes Care, 27: 1487-1495.
Direct Link  |  

Wang, M.Q., R.Z. Xu, L.Y. Zha and M.D. Lindemann, 2007. Effect of chromium nanocomposite supplementation on blood metabolites, endocrine parameters and immune traits in finishing pigs. J. Anim. Feed Sci., 139: 69-80.
Direct Link  |  

Wang, Z.Q., X.H. Zhang, J.C. Russell, M. Hulver and W.T. Cefalu, 2006. Chromium picolinate enhances skeletal muscle cellular insulin signaling in vivo in obese, insulin-resistant JCR:LA-cp rats. J. Nutr., 136: 415-420.
Direct Link  |  

Wild, S., G. Roglic, A. Green, R. Sicree and H. King, 2004. Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care, 27: 1047-1053.
CrossRef  |  PubMed  |  Direct Link  |  

Yamamoto, A., O. Wada and T. Ono, 1984. Distribution and chromium�binding capacity of a low�molecular�weight, chromium�binding substance in mice. J. Inorg. Biochem., 22: 91-102.
PubMed  |  

Yang, X., S.T. Li, F. Dong, J. Ren and N. Sreejayan, 2006. Insulin-sensitizing and cholesterol-lowering effects of chromium (D-phenylalaninine). J. Inorg. Biochem., 100: 1187-1193.
PubMed  |  

Zhao, C., P. Wang, X. Xiao, J. Chao, L. Chao, D.W. Wang and D.C. Zeldin, 2003. Gene therapy with human tissue kallikrein reduces hypertension and hyperinsulinemia in fructose-induced hypertensive rats. Hypertension, 42: 1026-1033.
Direct Link  |