References

Abdulmonem Al-Hayani 2011. The Efficacy of Antioxidative Therapy in Hepatic Fibrosis Induced Experimentally by Bile Duct Ligation in Rats J. Anim. Vet. Adv., 10: 764-773.
CrossRef  |  

Andoh, T., Q. Zhang, T. Yamamoto, M. Tayama, M. Hattori, K. Tanaka and Y. Kuraishi, 2010. Inhibitory effects of the methanol extract of Ganoderma lucidum on mosquito allergy-induced itch-associated responses in mice. J. Pharmacol. Sci., 114: 292-297.
CrossRef  |  PubMed  |  Direct Link  |  

Aydin, S., E. Aytac, H. Uzun, T. Altug and B. Mansur et al., 2010. Effects of Ganoderma lucidum on obstructive jaundice-induced oxidative stress. Asian J. Surg., 33: 173-180.
CrossRef  |  Direct Link  |  

Chang, Y.H., J.S. Yang, J.L. Yang, C.L. Wu and S.J. Chang et al., 2009. Ganoderma lucidum extracts inhibited leukemia WEHI-3 cells in BALB/c mice and promoted an immune response in vivo. Biosci. Biotechnol. Biochemis., 73: 2589-2594.
CrossRef  |  PubMed  |  Direct Link  |  

Chu, T.T., I.F. Benzie, C.W. Lam, B.S. Fok, K.K. Lee and B. Tomlinson, 2011. Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): Results of a controlled human intervention trial. Br. J. Nutr., 1: 1-11.
PubMed  |  Direct Link  |  

Chuang, H.Y., L.T. Ng, L.T. Lin, J.S. Chang, J.Y. Chen, T.C. Lin and C.C. Lin, 2011. Hydrolysable tannins of tropical almond show antifibrotic effects in TGF- β1-induced hepatic stellate cells. J. Sci. Food Agric., 91: 2777-2784.
CrossRef  |  Direct Link  |  

El-Lakkany, N.M., O.A. Hamam, W.H. El-Madawy, A.A. Badawy, A.A. Ain-Shoka and F.A. Ebeid, 2012. Anti-inflammatory/anti-fibrotic effects of the hepatoprotective silymarin and the schistosomicide praziquantel against Schistosoma mansoni-induced liver fibrosis. Parasit. Vectors Vol., 5. 10.1186/1756-3305-5-9

Jan, R.H., T.Y. Lin, Y.C. Hsu, S.S. Lee and S.Y. Lo et al., 2011. Immuno-modulatory activity of Ganoderma lucidum-derived polysacharide on human monocytoid dendritic cells pulsed with Der p 1 allergen. BMC Immunol. Vol. 12. 10.1186/1471-2172-12-31

Lang, Q., Q. Liu, N. Xu, K.L. Qian and J.H. Qi et al., 2011. The antifibrotic effects of TGF-β1 siRNA on hepatic fibrosis in rats. Biochem. Biophys. Res. Commun., 409: 448-453.
CrossRef  |  Direct Link  |  

Liang, Y.J., J. Luo, Q. Yuan, D. Zheng and Y.P. Liu et al., 2011. New insight into the antifibrotic effects of praziquantel on mice in infection with Schistosoma japonicum. PLoS ONE, Vol. 6, No. 5. 10.1371/journal.pone.0020247

Lin, W.C. and W.L. Lin, 2006. Ameliorative effect of Ganoderma lucidum on carbon tetrachloride-induced liver fibrosis in rats. World J. Gastroenterol., 12: 265-270.
PubMed  |  Direct Link  |  

Meng, J., X. Hu, F. Shan, H. Hua, C. Lu E. Wang and Z. Liang, 2011. Analysis of maturation of murine dendritic cells (DCs) induced by purified Ganoderma lucidum polysaccharides (GLPs). Int. J. Biol. Macromol., 49: 693-699.
CrossRef  |  PubMed  |  Direct Link  |  

Parsian, H., A. Rahimipour, M. Nouri, M.H. Somi and D. Qujeq, 2010. Assessment of liver fibrosis development in chronic hepatitis B patients by serum hyaluronic acid and laminin levels. Acta Clin. Croat., 49: 257-265.
PubMed  |  Direct Link  |  

Provenzano, M. and S. Mocellin, 2007. Complementary techniques: Validation of gene expression data by quantitative real time PCR. Adv. Exp. Med. Biol., 593: 66-73.
PubMed  |  Direct Link  |  

Rakotonirina, E.J., P. Andrianjaka, R.A. Rakotoarivelo, R.M. Ramanampamonjy, M.J. Randria and J.D. Rakotomanga, 2010. Relation between Shistosoma mansoni and hepatosplenomegalies. Sante, 20: 15-19.
PubMed  |  Direct Link  |  

Rygiel, K.A., H. Robertson, H.L. Marshall, M. Pekalski and L. Zhao et al., 2008. Epithelial-mesenchymal transition contributes to portal tract fibrogenesis during human chronic liver disease. Lab. Invest., 88: 112-123.
CrossRef  |  Direct Link  |  

Shi, Y., J. Sun, H. He, H. Guo and S. Zhang, 2008. Hepatoprotective effects of Ganoderma lucidum peptides against d-galactosamine-induced liver injury in mice. J. Ethnopharmacol., 117: 415-419.
CrossRef  |  PubMed  |  Direct Link  |  

Soliman, G.M., K.A. Mohammed, A. Taha and A.A. Barrak, 2010. The role of plasma transforming growth factor beta-1 in the development of fibrosis in patient with HCV related steatohepatitis. J. Egypt. Soc. Parasitol., 40: 759-772.
PubMed  |  Direct Link  |  

Subeq, Y.M., C.Y. Ke, N.T. Lin, C.J. Lee, Y.H. Chiu and B.G. Hsu, 2011. Valsartan decreases TGF-β1 production and protects against chlorhexidine digluconate-induced liver peritoneal fibrosis in rats. Cytokine, 53: 223-230.
CrossRef  |  PubMed  |  Direct Link  |  

Sudheesh, N.P., T.A. Ajith, V. Ramnath and K.K. Janardhanan, 2010. Therapeutic potential of Ganoderma lucidum (Fr.) P. Karst. against the declined antioxidant status in the mitochondria of post-mitotic tissues of aged mice. Clin. Nutr., 29: 406-412.
CrossRef  |  

Tache, D., F. Bogdan, C. Pisoschi, M. Banita, C. Stanciulescu, A.M. Fusaru and V. Comanescu, 2011. Evidence for the involvement of TGF- β1-CTGF axis in liver fibrogenesis secondary to hepatic viral infection. Rom. J. Morphol. Embryol., 52: 409-412.
PubMed  |  Direct Link  |  

Wang, G.J., Y.J. Huang, D.H. Chen, Y.L. Lin, 2009. Ganoderma lucidum extract attenuates the proliferation of hepatic stellate cells by blocking the PDGF receptor. Phytother. Res., 23: 833-839.
CrossRef  |  PubMed  |  Direct Link  |  

Weng, C.J., C.F. Chau, G.C. Yen, J.W. Liao, D.H. Chen and K.D. Chen, 2009. Inhibitory effects of Ganoderma lucidum on tumorigenesis and metastasis of human hepatoma cells in cells and animal models. J. Agric. Food Chem., 57: 5049-5057.
CrossRef  |  Direct Link  |  

Wu, Y.W., H.L. Fang and W.C. Lin, 2010. Post-treatment of Ganoderma lucidum reduced liver fibrosis induced by thioacetamide in mice. Phytother. Res., 24: 494-499.
CrossRef  |  PubMed  |  Direct Link  |  

Yeh, C.H., H.C. Chen, J.J. Yang, W.I. Chuang and F. Sheu, 2010. Polysaccharides PS-G and protein LZ-8 from Reishi (Ganoderma lucidum) exhibit diverse functions in regulating murine macrophages and T lymphocytes. J. Agric. Food Chem., 58: 8535-8544.
PubMed  |  Direct Link  |  

Zhang, J., Q. Tang, C. Zhou, W. Jia and L. Da Silva et al., 2010. GLIS, a bioactive proteoglycan fraction from Ganoderma lucidum, displays anti-tumour activity by increasing both humoral and cellular immune response. Life Sci., 87: 628-637.
CrossRef  |  Direct Link  |  

Zhao, L., C.R. Gandhi and Z.H. Gao, 2011. Involvement of cytosolic phospholipase A₂ alpha signalling pathway in spontaneous and transforming growth factor-beta-induced activation of rat hepatic stellate cells. Liver Int., 31: 1565-1573.
CrossRef  |  Direct Link  |