References

Agger, E.M. and P. Andersen, 2002. A novel TB vaccine: Towards a strategy based on our understanding of BCG failure. Vaccine, 22: 7-14.
PubMed  |  Direct Link  |  

Andersen, P. and T.M. Doherty, 2005. The success and failure of BCG-implications for a novel tuberculosis vaccine. Nat. Rev. Microbiol., 3: 656-656.
Direct Link  |  

Behr, M.A., M.A. Wilson, W.P. Gill, H. Salamon, G.K. Schoolnik, S. Rane and P.M. Small, 1999. Comparative genomics of BCG vaccines by whole-genome DNA microarray. Science, 284: 1520-1523.
PubMed  |  Direct Link  |  

Boyle, E.C., J.L. Bishop, G.A. Grassl and B.B. Finlay, 2007. Salmonella: From pathogenesis to therapeutics. J. Bacteriol., 189: 1489-1495.
Direct Link  |  

Brandt, L., J.F. Cunha, A.W. Olsen, B. Chilima, P. Hirsch, R. Appelberg and P. Andersen, 2002. Failure of the Mycobacterium bovis BCG Vaccine: Some species of environmental mycobacteria block multiplication of BCG and induction of protective immunity to tuberculosis. Infect Immun., 70: 672-677.
Direct Link  |  

Brandt, L., T. Oettinger, A. Holm, A.B. Andersen and P. Andersen, 1996. Key epitopes on the ESAT-6 antigen recognized in mice during the recall of protective immunity to Mycobacterium tuberculosis. J. Immun., 157: 3527-3533.
Direct Link  |  

Caruso, A., N. Serbina, E. Klein, K. Triebold, B. Bloom and J. Flynn, 1999. Mice deficient in CD4 T cells have only transiently diminished levels of IFN-gamma, yet succumb to tuberculosis. J. Immunol., 162: 5407-5416.
PubMed  |  Direct Link  |  

Chen, F., J. Zhou, F.L. Luo, A.B. Mohammed and X.L. Zhang, 2007. Aptamer from whole-bacterium SELEX as new therapeutic reagent against virulent Mycobacterium tuberculosis. Biochem. Biol. Res. Commun., 357: 743-748.
PubMed  |  Direct Link  |  

Curtiss, III R., 2002. Bacterial infectious disease control by vaccine development. J. Clin. Invest., 110: 1061-1066.
PubMed  |  Direct Link  |  

Feng, Y., S.Q. Wang, F.L. Luo, Y. Ruan and L. Kang et al., 2008. A novel recombinant bacterial vaccine strain expressing dual viral antigens induces multiple immune responses to the Gag and gp120 proteins of HIV-1 in immunized mice. Antiviral Res., 80: 272-279.
CrossRef  |  Direct Link  |  

Flynn, J.L., M.M. Goldstein, K.J. Triebold, B. Koller and B.R. Bloom, 1992. Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection. Proc. Natl. Acad. Sci. USA., 89: 12013-12017.
PubMed  |  Direct Link  |  

Formal, S.B., L.S. Baron, D.J. Kopecko, O. Washington and C. Powell et al., 1981. Construction of a potential bivalent vaccine strain: Introduction of Shigella sonnei form I antigen genes into the galE Salmonella typhi Ty21a typhoid vaccine strain. Infect. Immun., 34: 746-750.
Direct Link  |  

Franco-Paredes, C., N. Rouphael, C. del Rio and J.I. Santos-Preciado, 2006. Vaccination strategies to prevent tuberculosis in the new millennium: From BCG to new vaccine candidates. Int. J. Infec. Dis., 10: 93-102.
PubMed  |  Direct Link  |  

Geluk, A., M.Y. Lin, K.E. van Meijgaarden, E.M. Leyten and K.L. Franken et al., 2007. T-cell recognition of the HspX protein of Mycobacterium tuberculosis correlates with latent M. tuberculosis infection but not with M. bovis BCG vaccination. Infect. Immun., 75: 2914-2921.
PubMed  |  Direct Link  |  

Hoft, D.F., 2008. Tuberculosis vaccine development: Goals, immunological design, andevaluation. Lancet, 372: 164-175.
PubMed  |  Direct Link  |  

Hoiseth, S.K. and B.A. Stocker, 1981. Aromatic-dependent Salmonella typhimurium are nonvirulent and effective as live vaccines. Nature, 291: 238-239.
PubMed  |  Direct Link  |  

Kotton, C.N. and E.L. Hohmann, 2004. Enteric pathogens as vaccine vectors for foreign antigen delivery. Infect. Immun., 72: 5535-5547.
Direct Link  |  

Li, P.F., Q. Wan, Y. Feng, M. Liu and J.G. Wu et al., 2007. Engineering of N-glycosylation of Hepatitis C Virus Envelope Protein E2 Enhances T cell responses for DNA immunization. Vaccine, 25: 1544-1551.
PubMed  |  Direct Link  |  

Liao, X.L., H. Ren, P. Zhao, S.Y. Zhu and J. Cao et al., 2007. Efficient induction of mouse immune responses to hepatitis C virus by viral core protein-carrying attenuated Salmonella typhimurium. Viral. Immunol., 20: 469-478.
PubMed  |  Direct Link  |  

Lindsay, J.H., C.D.P. Simon and O.C.D. Simon, 2009. Characterisation of a live Salmonella vaccine stably expressing the Mycobacterium tuberculosis Ag85B-ESAT6 fusion protein. Vaccine, 27: 6894-6904.
Direct Link  |  

Parida, S.K., K. Huygen, B. Ryffel and T. Chakraborty, 2005. Novel bacterial delivery system with attenuated Salmonella typhimurium carrying plasmid encoding Mtb antigen 85A for mucosal immunization: Establishment of proof of principle in TB mouse model. Ann. NY Acad. Sci., 1056: 366-378.
PubMed  |  Direct Link  |  

Pym, A.S., P. Brodin, L. Majlessi, R. Brosch and C. Demangel et al., 2003. Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis. Nat. Med., 9: 533-539.
PubMed  |  Direct Link  |  

Roland, K.L., S.A. Tinge, K.P. Killeen and S.K. Kochi, 2005. Recent advances in the development of live, attenuated bacterial vectors. Curr. Opin. Mol. Ther., 7: 62-72.
PubMed  |  Direct Link  |  

Wang, Q.L., Q. Pan, Y.F. Ma and X.L. Zhang, 2009. An attenuated Salmonella-vectored vaccine elicits protective immunity against Mycobacterium tuberculosis. Vaccine, 27: 6712-6722.
CrossRef  |  Direct Link  |  

World Health Organization, 2006. Global tuberculosis control-surveillance, planning, financing. WHO Report, Geneva, Switzerland. http://www.who.int/tb/publications/global_report/2006/en/.

Zabolotnykh, N.V., T.I. Vinogradova, M.A. Stukova, S.N. Vasileva and M.L. Vitovskala et al., 2008. The effectiveness of influenza vectors expressing the protective mycobacterial antigen ESAT-6 in the complex therapy of generalized tuberculosis in mice. Probl. Tuberk. Bolezn. Legk., 12: 30-34.
PubMed  |  Direct Link  |