Abstract: Many governments in the economic crisis have been able to adopt measures and policies for the benefit of women workers on overcoming crises community and succeed in the course of development. Since, women constitute a large part of the society. Among women, the status of women-headed households is particularly important, since women heads of household are considered vulnerable therefore, this group of community entrepreneurship is of particular importance. This study seeks to identify and prioritize of entrepreneurship development ways for female-headed households who are under the protection of Imam Khomeini Relief Foundation in region 1 of Zahedan. The research method was descriptive survey. Statistical society includes all female-headed households who are under the protection of Imam Khomeini Relief Foundation in region 1 of Zahedan. That 327 people were selected as the sample then according to the data collected, those three factors and indicators of development of entrepreneurship as entrepreneurship development factors of female-headed householdswere identify and prioritized. Among three factors: environmental, structural, individual, personal factors are respectively ranked first with 9.23 and environmental factors are in second place with 6.96 and structural factors are third with 5.81. Another factor was identified individual contribution of more than two others and also among the main factors of motivation and perseverance Friedman test are respectively ranked first with 9.12 and self-sufficiency project is second with 8.65 and personality is ranked third with 7.88, family support in fourth with 7.55, social, cultural in fifth with 6.87, family circumstances housed in sixth place with 5.80, state institutions seventh in 4.87, social security insurance in eighth with 4.17 and the government is in ninth with 3.11.