Authors : A.I. Almubarak
Abstract: The effects of doxapram on respiratory rate, heart rate, Arterial Blood Pressure (ABP) and some haematology and biochemistry parameters were carried out on six camels in two periods. In the first period, all camels received Intravenous (IV) 0.2 mg kg-1 xylazine while in the second period, same camels received IV 0.4 mg kg-1 doxapram, followed 10 min later by IV 0.2 mg kg-1 xylazine. Cardiopulmonary measurements were taken at baseline and were further recorded at 10, 20, 30, 40, 50 and 60 min after treatment in both periods. Mean respiratory rate, heart rate and ABP measurements decreased significantly after xylazine in the first period. Mean respiratory rate in the second period increased significantly at 10 min while systolic ABP increased significantly at 30 min when compared with first period. Mean heart rate decreased significantly at 20 min in the second period when compared with first period. There was a significant differences between the two periods in some measured haematological and biochemical parameters. Doxapram was useful to increase respiratory rate and ABP in xylazine sedated camels. Higher doses of doxapram needed further investigation in camels.
A.I. Almubarak , 2012. Evaluation of Intravenous Administration of Doxapram Prior to Xylazine Sedation in Camels (Camelus dromedarius). Journal of Animal and Veterinary Advances, 11: 4455-4459.