Authors : Abolghasemi Esmail, Moosa-Kazemi Seyed Hassan, Abolghasemi Fatemeh, Abolhasani Mandan, Khodaei Homa and Davodi Maryam
Abstract: Human NPH insulin (Lansulin N) considered as anti-diabetes drug. In addition, symmetrel (amantadine hydrochloride) found as anti-virus and anti-Parkinson drug which the mortality effects of the drugs was the study against Blattela germanica. German cockroaches were reared at 25±20°C, 40-50% RH and 14L:10D photoperiod cycle. The concentration of 5, 10, 15, 20 and 25 μL of Human NPH insulin (Lansulin N) and 0.5, 1, 2, 4 and 8% of symmetrel (amantadine hydrochloride) was used. The data were analyzed using SPSS software. p<0.05 was considered significant as the difference between groups. Dose of 20 μL of Lansulin N causing death among the 63.34% of the samples in addition, 86.67% of German cockroaches killed after the exposure with 2% dose of the amantadine hydrochloride. There is significant mortality was found between the doses of 2% with comparing to another doses (p<0.05). In significant mortality found after exposure with 20 μL of Lansulin N with comparing the other dose (p<0.05). The dose of 2% amantadine hydrochloride and 20 μL Lansulin N cause reduces irritability, weakness and eventual death of these cockroaches. The researchers suggested that the appropriate doses of these drugs as a poisoned bait or gel used against the wild strain of B. germanica in the future.
Abolghasemi Esmail, Moosa-Kazemi Seyed Hassan, Abolghasemi Fatemeh, Abolhasani Mandan, Khodaei Homa and Davodi Maryam, 2011. Mortality Effects of Human NPH Insulin (Lansulin N) and Symmetrel (Amantadine Hydrochloride) on German Cockroach: Blattela germanica (L.). Research Journal of Biological Sciences, 6: 304-308.