Authors : Yunyun Zhou, Changzheng Chen, Ying Chen, Yi Zuohuizi, Ming Weng, Qi Hang and Yiqiao Xing
Abstract: The objective is to evaluate the clinic characteristics of patients with choroidal folds. A retrospective study of 39 patients (68 eyes) with choroidal folds. All the subjects underwent Fluorescence Angiography (FA), however only parts of them underwent Indocyanine Green Angiography (ICGA) and Optical Coherence Tomography (OCT). There were 24 patients with uveitis, of which 12 were Vogt-Koyanagi-Harada disease (VKH). Choroidal folds appeared as alternating light and dark streaks in the pole. On FA examination, the folds showed almost parallel bands of either hypofluorescence or hyperfluorescence. The remarkable thing is that two types of choroidal folds-coarse folds and wrinkles were observed on FA. On ICGA examination, choroidal folds showed either normal or hypofluorescent at early stages and showed either hyperfluorescent or hypofluorescent at late stages. OCT can directly display morphological characteristics of choroidal folds in some patients and the folds involve the Retinal Pigment Epithelium (RPE) and choroidal layer. Uveitis, especially VKH, researchers suspect is the main cause of choroidal folds in Chinese patients. The two types of choroidal folds were noted on FA which are coarse folds and wrinkles.
Yunyun Zhou, Changzheng Chen, Ying Chen, Yi Zuohuizi, Ming Weng, Qi Hang and Yiqiao Xing, 2013. Clinical Observations Concerning Choroidal Folds in Chinese Patients. Research Journal of Biological Sciences, 8: 133-137.