Authors : Manmohan Singhal and Parul Srivastava
Abstract: Lymph nodes are organ and widely distributed in different parts of the body where innate immune responses lead to acquired immunity where autoreactive lymphocytes first encounter tissue-specific self-antigens and are either tolerized or activated. Lymph nodes respond well to mitogens (Concanavalin A) and alloantigens and stimulate the T-lymphocyte proliferation and activate the IL-2 surface receptor for expression of IL-2 in vitro. The present review aimed to discuss the pattern of expression of IL-2 and the effect of Concanavalin A in lymph nodes.
Manmohan Singhal and Parul Srivastava, 2013. Effect of Concanavalin A on IL-2 Expression from Lymph Node Cells. Research Journal of Medical Sciences, 7: 102-109.