Abstract: A field study was carried out to determine the incidence of twig die back on young cashew plots and its control using the combination of a fungicide and an insecticide. The cashew plot used for the study which was originally established to study the plant performance as affected by nut-size and planting method, was a split plot laid out in randomized complete block with 3 replications. A mixture of Unden 20EC (an insecticide) and Champ D-P (a copper-based fungicide) at 4.0 mL 1: 4 gL 1 respectively was monthly sprayed for 4 months while unsprayed cashew trees, 3 m away from the sprayed treatments served as control. Data were collected on the infection (%) and the effectiveness of the sprayed chemical mixture. This was done for 4 months. The result showed that the cashew plants raise from Madras Nut-Size (MANS) (6-8 g) and Jumbo Nut-Size (JUNS) (>16g) had 60.5 and 58.2%, respectively. Between 1 and 3 Months After Spraying (MAS), the disease incidence ranged between 31.8 and 28.8% for MANS, 34.9 and 25.3% for MENS and 29.0 and 19.6% for JUNS treated cashew plants, respectively. In non-treated cashew plant, the disease incidence ranged between 40.8 and 26.7% for MANS and 44.1 and 34.3% for MENS and 44.2 and 29.8% for JUNS, respectively. The reduction in disease incidence in non-treated cashew plants was due to the slow natural recovery of the plant. The planting method had no effect on the disease incidence.