References

Bao, L., A. Haque, K. Jackson, S. Hazari, K. Moroz, R. Jetly and S. Dash, 2011. Increased expression of p-glycoprotein is associated with doxorubicin chemoresistance in the metastatic 4T1 breast cancer model. Am. J. Pathol., 178: 838-852.
CrossRef  |  Direct Link  |  

Conrad, D.M., S.J. Furlong, C.D. Doucette, K.A. West and D.W. Hoskin, 2010. The Ca ²⁺ channel blocker flunarizine induces caspase-10-dependent apoptosis in Jurkat T-leukemia cells. Apoptosis, 15: 597-607.
CrossRef  |  

Di Sabatino, A., L. Rovedatti, R. Kaur, J.P. Spencer and J.T. Brown et al., 2009. Targeting gut T cell Ca²⁺ release-activated Ca²⁺ channels inhibits T cell cytokine production and T-box transcription factor T-bet in inflammatory bowel disease. J. Immunol., 183: 3454-3462.
CrossRef  |  

Dressel, A., M. Kwari and A.M. McGreal, 2011. Nursing considerations for optimal outpatient management of adult patients with leukemia treated with clofarabine. Clin. J. Oncol. Nurs., 15: E13-E23.
CrossRef  |  

Farias, E.F., J.A.A. Ghiso, V. Ladeda and E.B.D.K. Joffe, 1998. Verapamil inhibits tumor protease production, local invasion and metastasis development in murine carcinoma cells. Int. J. Cancer, 78: 727-734.
CrossRef  |  

Grujic, M. and M. Renko, 2002. Aminopeptidase inhibitors bestatin and actinonin inhibit cell proliferation of myeloma cells predominantly by intracellular interactions. Cancer Lett., 182: 113-119.
CrossRef  |  

Gupta, V., N. Kamath, G.T. Tkalcevic and S.V. Singh, 1994. Potentiation of tamoxifen activity by verapamil in a human breast cancer cell line. Biochem. Pharmacol., 47: 1701-1704.
CrossRef  |  

Hajighasemi, F. and A. Mirshafiey, 2010. Propranolol effect on proliferation and vascular endothelial growth factor secretion in human immunocompetent cells. J. Clin. Immunol. Immunopathol. Res., 2: 22-27.
Direct Link  |  

Iskenderov, B.G., O.N. Sisina and L.F. Burmistrova, 2011. Selection of rational combinations of indapamide with various of calcium antagonists in patients with arterial hypertension. Kardiologiia, 51: 22-27.
PubMed  |  

Kameda, K., T. Kondo, K. Tanabe, Q.L. Zhao and H. Seto, 2001. The role of intracellular Ca²⁺ in apoptosis induced by hyperthermia and its enhancement by verapamil in U937 cells. Int. J. Radiat. Oncol. Biol. Phys., 49: 1369-1379.
CrossRef  |  

Khwaja, A., 2010. PI3K as a target for therapy in haematological malignancies. Curr. Top. Microbiol. Immunol., 347: 169-188.
CrossRef  |  

Kim, Y.K., N.H. Kim, J.W. Hwang, Y.J. Song and Y.S. Park et al., 2008. Histone deacetylase inhibitor apicidin-mediated drug resistance: involvement of P-glycoprotein. Biochem. Biophys. Res. Commun., 368: 959-964.
CrossRef  |  

Koo, J.S., W.C. Choi, Y.H. Rhee, H.J. Lee and E.O. Lee et al., 2008. Quinoline derivative KB3-1 potentiates paclitaxel induced cytotoxicity and cycle arrest via multidrug resistance reversal in MES-SA/DX5 cancer cells. Life Sci., 83: 700-708.
CrossRef  |  

Kostis, W.J., W.M. Suh and I.F. Palacios, 2011. Acute myocardial infarction caused by multivessel coronary spasm due to calcium channel blocker withdrawal. Catheter. Cardiovasc. Interv., 78: 229-233.
CrossRef  |  

Li, G., X.P. Qi, X.Y. Wu, F.K. Liu and Z. Xu et al., 2006. Verapamil modulates LPS-induced cytokine production via inhibition of NF-kappa B activation in the liver. Inflamm. Res., 55: 108-113.
CrossRef  |  

Li, W., S.L. Zhang, N. Wang, B.B. Zhang and M. Li, 2011. Blockade of T-type Ca²⁺ channels inhibits human ovarian cancer cell proliferation. Cancer Invest., 29: 339-346.
CrossRef  |  

Liu, R., Y. Zhang, Y. Chen, J. Qi and S. Ren et al., 2010. A novel calmodulin antagonist O-(4-Ethoxyl-Butyl)-Berbamine overcomes multidrug resistance in drug-resistant MCF-7/ADR breast carcinoma cells. J. Pharm. Sci., 99: 3266-3275.
PubMed  |  

Liu, Y., Y.C. Lo, L. Qian, F.T. Crews and B. Wilson et al., 2011. Verapamil protects dopaminergic neuron damage through a novel anti-inflammatory mechanism by inhibition of microglial activation. Neuropharmacology, 60: 373-380.
CrossRef  |  PubMed  |  

Liu, Y., Z. Lu, P. Fan, Q. Duan and Y. Li et al., 2011. Clinical efficacy of chemotherapy combined with verapamil in metastatic colorectal patients. Cell Biochem. Biophys., 61: 393-398.
CrossRef  |  PubMed  |  

Matsumori, A., R. Nishio and Y. Nose, 2010. Calcium channel blockers differentially modulate cytokine production by peripheral blood mononuclear cells. Circ. J., 74: 567-571.
PubMed  |  

Meister, S., B. Frey, V.R. Lang, U.S. Gaipl, G. Schett, U. Schlotzer-Schrehardt and R.E. Voll, 2010. Calcium channel blocker verapamil enhances endoplasmic reticulum stress and cell death induced by proteasome inhibition in myeloma cells. Neoplasia, 12: 550-561.
CrossRef  |  PubMed  |  Direct Link  |  

Moldeus, P., J. Hogberg and S. Orrenius, 1978. Isolation and use of liver cells. Methods Enzymol., 52: 60-71.
PubMed  |  Direct Link  |  

Mosmann, T., 1983. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J. Immunol. Methods, 65: 55-63.
CrossRef  |  PubMed  |  Direct Link  |  

Pingsheng, F., Z. Tengyue, H. Qiang, W. Qiang, S. Xin and Q. Liting, 2012. Basic and clinical research on the therapeutic effect of intervention in primary liver cancer by targeted intra-arterial verapamil infusion. Cell Biochem. Biophys., 62: 59-67.
CrossRef  |  PubMed  |  

Satoh, E. and R. wasaki, 2011. Experimental diabetes attenuates calcium mobilization and proliferative response in splenic lymphocytes from mice. J. Physiol. Sci., 61: 23-30.
CrossRef  |  PubMed  |  

Skal'skii, S.V., 2010. Effect of verapamil on production of anti-inflammatory cytokines by peritoneal mononuclears. Vestn. Ross. Akad. Med. Nauk., 3: 33-35.
PubMed  |  

Song, X.R., Y. Zheng, G. He, L. Yang and Y.F. Luo et al., 2010. Development of PLGA nanoparticles simultaneously loaded with vincristine and verapamil for treatment of hepatocellular carcinoma. J. Pharm. Sci., 99: 4874-4879.
CrossRef  |  PubMed  |  

Vogler, M., D. Dickens, M.J. Dyer, A. Owen, M. Pirmohamed and G.M. Cohen, 2011. The B-cell lymphoma 2 (BCL2)-inhibitors, ABT-737 and ABT-263, are substrates for P-glycoprotein. Biochem. Biophys. Res. Commun., 408: 344-349.
CrossRef  |  PubMed  |  

Wang, F., D. Zhang, Q. Zhang, Y. Chen and D. Zheng et al., 2011. Synergistic effect of folate-mediated targeting and verapamil-mediated P-gp inhibition with paclitaxel -polymer micelles to overcome multi-drug resistance. Biomaterials, 32: 9444-9456.

Wang, J.C., X.Y. Liu, W.L. Lu, A. Chang, Q. Zhang, B.C. Goh and H.S. Lee, 2006. Pharmacokinetics of intravenously administered stealth liposomal doxorubicin modulated with verapamil in rats. Eur. J. Pharm. Biopharm., 62: 44-51.
CrossRef  |  PubMed  |  

Xia, X., J. Yang, F. Li, Y. Li, X. Zhou, Y. Dai and S.T. Wong, 2010. Image-based chemical screening identifies drug efflux inhibitors in lung cancer cells. Cancer Res., 70: 7723-7733.
CrossRef  |  PubMed  |  

Yanamandra, N., R.W. Buzzeo, M. Gabriel, L.A. Hazlehurst, Y. Mari, D.M. Beaupre and J. Cuevas, 2011. Tipifarnib-induced apoptosis in acute myeloid leukemia and multiple myeloma cells depends on Ca²⁺ influx through plasma membrane Ca²⁺ channels. J. Pharmacol. Exp. Ther., 337: 636-643.
CrossRef  |  PubMed  |  

Zhang, Y., J. Tao, H. Huang, G. Ding, Y. Cheng and W. Sun, 2007. Effects of celecoxib on voltage-gated calcium channel currents in rat pheochromocytoma (PC12) cells. Pharmacol. Res., 56: 267-274.
PubMed  |